Microneedles: an Innovative Approach to Transdermal Delivery- a Review

Transdermal delivery holds a promising carrier in the transport of drugs to get direct access across the skin deep into the systemic circulation.. It has attracted many researchers due to various biomedical advantages. The barrier nature of stratum corneum poses a threat to the drug delivery. However, various attempts have been made to modify this property of the skin and thus, to improve the transdermal delivery. Delivery of drugs via transdermal route has proved to be the convenient route for various clinical implications. Due to the limitation of oral drug delivery and the pain related with the use of needles in case of injections, drug delivery research has tremendously oriented towards the transdermal route The objective of the present review is to focus on the recent innovations in transdermal drug delivery systems which can serve as a platform for the research and development of pharmaceutical drug dosage form for efficient transdermal delivery. It also focuses on the delivery of various therapeutic agents effectively via different carriers emphasizing mainly on the potential role of microneedles as transdermal system. Researches in the past few years showed that microneedles have emerged as a novel carrier and considered to be effective for improved and safe delivery of drugs. Thus, it was concluded that the development of microneedles created a new pathway in the field of drug delivery.